Archive for the ‘Back Pain’ Category

Male Osteoporosis ” Part Two

Thyroid hormones can speed up the bone turnover rate if they are at abnormally high levels which make the incidence of osteoporosis more likely although it is relatively simple to medically treat the person to maintain normal thyroid hormone levels. Men with osteoporosis who are given to high levels of alcohol consumption are about 5 percent of all male osteoporosis sufferers and their chance of developing a hip fracture is three times that of someone who does not consume alcohol. Alcohol suppresses the activity of cells which produce bone substance and also inhibits the absorption of calcium and other nutrients, all fitting together with the tendency to be unsteady to add up to significant bone loss plus a risk of falling over.

Stomach surgery and gastrointestinal tract diseases make the likelihood of developing osteoporosis more likely but the precise reason for this is not certain. Being intolerant to gluten in the diet, known as coeliac disease, initiates intestinal lining inflammation and this leads to the absorption of vitamins and minerals being poor. In a study of patients with coeliac disease, half were found to have low bone density despite following the correct diet.

If the risk to an individual of developing osteoporosis is higher than a certain level then a measurement of bone density may be requested. Bone density has to drop by 30% at least before the results show up on an x-ray so this is not a good way of estimating bone loss or monitoring it over time. DEXA scanning (Dual Energy X-ray Absorptiometry) is a much more reliable and sensitive method of calculating bone loss and following the changes which might occur with treatment. The level of bone density on DEXA scanning correlates well with the risk of fracturing and it is a very easy, safe and convenient technique due to the low radiation levels used and lack of undressing.

Treatment may be prescribed by a rheumatological specialist or a general practitioner on the basis of a risk factor, fracture incidence or on the results of a scan. The results of a scan are checked against typical average results and overall fall into the osteoporotic, osteopoenic or normal ranges. Since many individual conditions can alter bone density in men these will be diagnosed, investigated and treated as they can have large effects in improving bone stock. Replacement therapy for testosterone can be as patches, injections, implants or tablets but this treatment is not risk free and discussion with a medical adviser is recommended.

Bone breakdown cells or osteoclasts are responsible for bone removal and their actions are slowed down by a class of drugs known as bisphosphonates. This permits the osteoblasts or bone building cells to work with so much opposition and increase the bone mass. Common drugs are called alendronate, etidronate and risedronate. In very acute spinal fractures there is very severe pain and calcitonin is used which again interferes with osteoclasts and gives pain relief. If a muscle developing effect is required then anabolic steroids can be used to boost both that and bone density. Calcium and supplementation with vitamin D is used in men but the specific role in not clear but is covered by having an appropriate diet and some exposure to sunlight.

Maintaining a healthy bone density can be part of our individual responsibility and diet and exercise are two important factors. Even though much of our bone density is determined by genetic factors, we can alter it by our behaviour. A well balanced diet is typically recommended by choosing from four different groups of foods: cereals and breads; fruit and vegetables; milk and other dairy products; eggs, pulses, nuts, meat and fish. A sufficient calcium intake is vital with dairy products such as milk and cheese particularly high in this mineral.

Being an active tissue, bones respond to not being used by losing some of the strength which does not seem to be necessary. Weight bearing exercise causes regular impacts onto the bone, stimulating it to maintain itself or get denser. Examples of useful exercise are fast walking, running, weight training, aerobics, tennis and skipping, all impact activities. Swimming and cycling do not give this impact effect so are less useful. A typical recommendation is to perform suitable exercise for 20 minutes continuously three times a week for best results. New treatments are continually being developed for drugs and exercise therapy.

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Plating of Fractures

Because of the large number of locations where fractures occurs and the different bones involved there is a variety of plates available. The dynamic compression plate or DCP allows a sliding technique to be used because of the screw holes being angled away from a central point. Once the screws are inserted and tightened they apply an inwards compression force, bringing the fragments into stronger contact. The ulna and the ankle lateral malleolus are fixed with thin plates of about one mm in thickness which can be shaped to the area required. Fractures close to a joint need specially designed plates to facilitate fixation and reduce impingement.

Fractures of the upper femur are fixed by using plates with a 95 degree angle so that the mechanical axis of the upper femur can be restored at this angle. Inserting this kind of fixation requires that the surgeon thinks in three dimensions as are all must be correctly aligned to restore normal anatomy. Reconstruction plates are less thick than dynamic compression plates and can be contoured in three dimensions for the acetabulum and pelvis. Fractures close to or next to prostheses such as hip replacements or knee replacements are fixed with larger plates with the addition of cerclage wires.

High levels of fracture stability can be provided by compression of the fragments and a good restoration of anatomical alignment by the fixation. If firmly stabilised and without any fragment gap then the fracture will heal by primary healing. Absorption of the dead bone at the site of fracture occurs by the action of osteoclasts, with blood vessels growing into the region and then bone producing cells proliferating. Disruption of the blood supply by the plate can produce some osteoporosis under the plate, leading to reduced bone strength from this and the screw holes once the plate is removed, necessitating careful decisions about the amounts of force to be applied to the area.

The initial part of performing internal fixation is the exposure of the fracture site and the removal of the accumulated haematoma, followed by aligning the fragments as close to their original position as possible. Fracturing a bone disrupts the blood supply and the periosteal membrane provides the remaining blood supply to the area, a blood supply the surgeons take care not to disrupt by stripping the membrane from the bone during operation. This could delay the healing process due to reduction of blood supply. Fractures which are unstable or have multiple fragments have to be spanned by a bridge plate to restore bone length, rotation and alignment although this fixation cannot take significant load.

The LISS (Less Invasive Surgical Stabilisation) plating system is a recently developed technique which reduces the contact between the metal and the bone or periosteum, reducing the potential for disruption of the blood supply in the fracture area. Modern designs contour more effectively to the bony anatomy and allow for locking of the screws, which are both advantageous by maintaining the fracture in the correct position whilst allowing increased forces to be applied to it in the healing period. These new designs are most useful in fixing the ends of the bones in fractures of the tibia, femur, radius and humerus.

Conventional plating techniques are adequate to fix fractures where access to the areas is easy and in cases where the fractures are of a stable type, incorporating fractures of bony shafts such as the ulna, humerus and radius. With osteoporotic bone and difficult fixation options the locking systems will be more appropriate. As they are much more expensive than the conventional systems they are not yet the default choice in all cases but look likely to be more widely used as the cost comes down. They may well be cost effective if cases of malunion which require revision are taken into account.

Nails

Nailing techniques were standardised in the 1930s by Kuntscher, who made them the default management options for femoral shaft fractures, the option gradually being extended to breaks in the tibia and humerus as well as femoral fractures nearer the bone ends. Inserting a nail stabilises the fracture for early joint mobilisation and ambulation.

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Functions Of The Liver, Gallbladder, And Pancreas

There are three added organs yield allotment in assimilation of the aliment are the liver, the gallbladder, and the pancreas.

FUNCTION OF THE LIVER:

The alarmist is amid in the appropriate high division or RUQ of the abdomen. The alarmist creates an yellowish-brown black or greenish, blubbery aqueous alleged bile. Acerbity contains a blubbery actuality i.e. cholesterol, acerbity acids, and abounding acerbity pigments. The colorant alleged bilirubin is bogus from the breakdown of claret in the liver. Acerbity combines with bilirubin in the alarmist and afresh passes into the duodenum. This actual is aswell excreted out from the physique with feces.

The acerbity is accomplishment continuously in the alarmist campaign down to the gallbladder via hepatic aqueduct and cystic duct. Gallbladder is a pear-shaped sac like structure, which is beneath the liver. Gallbladder collects the acerbity and stored inside. The acerbity gets concentrated in the gallbladder. The acerbity affected to out to the duodenum via accepted acerbity aqueduct and pancreatic duct. The duodenum or the aboriginal allotment of the baby civil receives a admixture of acerbity and pancreatic juice.

Emulsification is an aftereffect of acerbity on fats in the duodenum, by which acerbity break ample fat globules and afresh the enzymes from the pancreas can abstract the fats. So fat assimilation is the important action of the bile. Without acerbity fat abstracts from the aliment will abide undigested. The alarmist afar from bearing bile, which aswell participates abounding important functions in animal body.

The alarmist maintains the bulk of claret sugars aswell alleged glucose accustomed in the physique by removing balance of sugars from the bloodstream and aliment it in the anatomy of starch (glycogen) in the alarmist cells. In the bearings of actual low claret sugars in the blood, which is a crisis action to the body, the glycogens or the starch are adapted afresh to the glucose by the liver. This action is alleged glycogenesis.

Another important action of the alarmist is aswell to catechumen fats and proteins in the physique into glucose and uses it if the physique needs it. This action is alleged gluconeogenesis. The alarmist aswell produces the important claret proteins capital for claret clotting. Bilirubin is produced by the alarmist abolition of old erythrocytes. The alarmist aswell removes the adulteration abstracts from the claret through a action alleged detoxification.

The addition important action of the alarmist is accumulation of urea. The alarmist receives amino acids from the claret and it removes ammonia and which is adapted into urea, and removed by branch and excreted out with urine.

The alarmist helps in the assimilation of fats via bile.

The alarmist aswell helps in authoritative physique temperature. It aliment hematrin all-important for the accumulation of RBCs. It forms RBC in the fetal life. It is a armory for abounding chemicals enzymes, and substances activity vitamins etc.

Hepatic Aperture System:

The claret argosy that accompany to the alarmist from the intestines. This arrangement of claret argosy is alleged hepatic aperture system.

Digested foods canyon into the aperture attitude anon afterwards getting captivated into the bloodstream from the baby intestine, appropriately giving the alarmist aboriginal adventitious at application the nutrients.

Functions of the pancreas:

The pancreas is an gland, which works both as an endocrine and aswell as an exocrine organ. As an exocrine, the pancreas produces pancreatic juices abounding with enzymes alleged amylase and lipase to abstract the food. These canyon into the duodenum through the pancreatic duct.

As an endocrine gland, the pancreas secretes insulin into the bloodstream. Insulin is a hormone capital to advice absolution amoroso from the blood, which acts as a carrier to accompany glucose into beef of the physique to be acclimated for energy.

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